This website is a place to share and exchange documentation, information, and resources on how to increase the value of both basic and applied research and reduce or avoid wasting research. It is based on a series of articles that were published in the medical journal The Lancet in 2014.










(Figure  Stages of waste in the production and reporting of research evidence relevant to clinicians and patients; from Chalmers & Glasziou, The Lancet 2009)

It has been estimated that 85% of research is wasted, usually because it asks the wrong questions, is badly designed, not published or poorly reported. While this primarily diminishes the value of research, it also represents a significant financial loss: it has been estimated that more than US$ 100,000,000,000 were wasted in Life Sciences research in 2009. However, many causes of this waste are simple problems that could easily be fixed, such as appropriate randomisation or blinding of a clinical trial. A first step towards increasing the value of research and reducing waste is to monitor the problems and develop and implement solutions that aim to fix them.

series of five papers about research report in The Lancet on the most pressing issues, recommend how to increase value and reduce waste in biomedical research, and propose metrics for stakeholders to monitor the implementation of these recommendations.

news and blog section and an event calendar keep you up-to-date with the latest developments on relevant topics  and a resource section provides links to other websites and tools that aim to increase the value of research.

This information will hopefully help to answer the right questions in research, address uncertainty in clinical practice and ultimately improve patient outcomes.

About the Authors

This website was created and is maintained by the lead authors of the Lancet series (Iain Chalmers, John Ioannidis, Malcolm Macleod, Rustam Al-Shahi Salman, An-Wen Chan, Paul Glasziou AO)

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