Key Recommendations

The Lancet article series includes a set of 17 recommendations for how to increase value and reduce waste in research. The most important are:

1. “Research funders should make information available about how they decide what research to support, and fund investigations of the effects of initiatives to engage potential users of research in research prioritisation.

• Monitoring—periodic surveys of information on research funders’ websites about their principles and methods used to decide what research to support”

2. “Research funders and regulators should demand that proposals for additional primary research are justified by systematic reviews showing what is already known, and increase funding for the required syntheses of existing evidence.

• Monitoring—audit proposals for and reports of new primary research”.

3. “Make publicly available the full protocols, analysis plans or sequence of analytical choices, and raw data for all designed and undertaken biomedical research.

• Monitoring—proportion of reported studies with publicly available (ideally preregistered) protocol and analysis plans, and proportion with raw data and analytical algorithms publicly available within 6 months after publication of a study report”.

4. “Reward (with funding, and academic or other recognition) reproducibility practices and reproducible research, and enable an efficient culture for replication of research.

• Monitoring—proportion of research studies undergoing rigorous independent replication and reproducibility checks, and proportion replicated and reproduced”.

5. “Regulators and policy makers should work with researchers, patients, and health professionals to streamline and harmonise the laws, regulations, guidelines, and processes that govern whether and how research can be done, and ensure that they are proportionate to the plausible risks associated with the research.


• Monitoring—regulators, individuals who govern and manage research, and researchers should measure and report delays and inconsistencies that result from failures to streamline and harmonise regulations”

6. “Funders, sponsors, regulators, research ethics committees, journals, and legislators should endorse and enforce study registration policies, wide availability of full study information, and sharing of participant-level data for all health research.

• Monitoring—assessment of the proportion of stakeholder policies that endorse dissemination activities, and the proportion of studies that are registered and reported with available protocols, full study reports, and participant-level data”.

7. “Research funders should take responsibility for reporting infrastructure that supports good reporting and archiving.

• Monitoring—funders and research institutions should regularly report expenditures for reporting infrastructure and archiving”.



Download file summarising all recommendations to increase value and reduce waste in research here.